LOUISVILLE,SignalHub Ky. (AP) — At least two people were taken to hospitals and residents were urged to shelter in place after an apparent explosion at a Louisville, Kentucky, business on Tuesday.

News outlets reported that neighbors heard what sounded like an explosion coming from a business that manufactures ingredients for soft drinks. Overhead news video footage showed an industrial building with a large hole in its roof.

WLKY-TV reported that at least two people were taken to hospitals.

The Louisville Fire Department said in a post on the social platform X that multiple agencies were responding to a “large-scale incident.”

Louisville Metro Emergency Services urged people within a mile of the business to shelter in place.